It means your transactions is out of balance. You need to print the out of balance report identify the issue and then use GL-P to add, delete or edit transactions needed to make GL-O balance.

You can either print it from GL-O by selecting everything processing and clicking on the Print Out of Bal Report button or you can print it from AM-R.  
 
AM-R Out of Balance Report
Purpose of Program
 
Use this program to identify out of balance entries in either the posted or unposted GL Transactions.  This is the same report called from GL-O  Print/Post General Ledger Batches in stand-alone form so it can be run without waiting for GL-O to scan all the unposted transactions.
 
General Program Operation

Enter a date range and select either posted or unposted transactions.  Any journal grouping of transactions within the date range that does not balance when matched by date, journal type and Cus/Vend Cod and Invoice #.  In some cases, the report will list entries that truly do balance but different sides of the entry list a different Customer or Vendor code or invoice number so you may need to manually eliminate such groups.

You need to use GL-P and edit the entry to get it into balance.

Just for clarification so I don't mess this up. On the Gl/O pop-up where it says -  
 
The last 75 transactions are causing the file to be out of balance...... Do you wish to exclude these items and post them later Y/N.
 
Do I want to go ahead and select No before I go to the GL/P to make the correction?
 
Jere'

Thanks for answering all my questions, so appreciated.  I am in balance and good to go.