We recently upgraded our server to 2008 and upgraded pervasive also to V10-- most users are better off but I am one who is not.  
 
Everything, including start up is slow as molasses.  Once I get a program open things seem okay.
It's the actual opening of the program or sub-program (SO-A, IN-A etc) that can take up to a minute or two.
 
 I notice on opening Evo that if I click on the first splash screen (continue) the splash screen appears again and I see in the lower left corner a flash of a program tasform(?)   I don't remember seeing that in the past when my connection was working.
 
My network guys are stumped and so am I.  Does anyone have any suggestions?

Thanks, Colin, I had a network problem but I had also changed my antivirus software and I think your suggestion definitely helped also.  
Too many changes all at once.